Doctor's Best Fully Active B Complex with Quatrefolic | 60 Veggie Caps

All eight B vitamins in their most bioavailable, active forms — including Quatrefolic®, the gold standard in folate supplementation.

Most B complex supplements use cheap, synthetic forms of B vitamins that your body must first convert before it can use them — a process that many people, particularly those with MTHFR gene variants, struggle to do efficiently. Doctor’s Best Fully Active B Complex skips the conversion step entirely. Every B vitamin is delivered in its biologically active form, ready for your cells to use immediately. The standout is Quatrefolic® — the most bioavailable form of folate available, providing superior stability and water solubility compared to standard folic acid. One capsule a day supports energy production, DNA integrity, nervous system health, and cellular metabolism from the ground up.

Key Benefits

• All 8 B vitamins in fully active, bioavailable forms — no conversion required
• Supports sustained energy production and reduces fatigue at the cellular level
• Supports DNA integrity, cell division, and healthy new cell formation
• Supports nervous system health, mood, and cognitive function
• Quatrefolic® folate — superior bioavailability vs standard folic acid, ideal for those with MTHFR variants
• Methylcobalamin B12 (1,000 mcg) — the active, neurologically preferred form
• Active B2 (riboflavin-5-phosphate) and B6 (pyridoxal-5-phosphate) for enhanced absorption
• Supports skin, hair, and immune health
• Non-GMO, vegan, gluten free, soy free
• 60 veggie capsules — 2-month supply at 1 capsule per day

Formula Highlights

• Vitamin B1 — Thiamin HCl (60 mg, 5,000% DV): Supports energy metabolism and nerve function
• Vitamin B2 — Riboflavin & Riboflavin-5-Phosphate (75 mg, 5,770% DV): Active form for superior absorption; supports energy and antioxidant function
• Vitamin B3 — Niacinamide & Niacin (50 mg, 310% DV): Supports energy production, DNA repair, and skin health
• Vitamin B6 — Pyridoxine HCl & Pyridoxal-5-Phosphate (50 mg, 2,940% DV): Active P5P form; supports neurotransmitter synthesis and hormone balance
• Folate — Quatrefolic® (400 mcg DFE, 100% DV): (6S)-5-methyltetrahydrofolic acid glucosamine salt — the most bioavailable folate form; supports DNA, cell division, and cardiovascular health
• Vitamin B12 — Methylcobalamin (1,000 mcg, 41,670% DV): The neurologically active form of B12; supports nerve health, energy, and red blood cell formation
• Biotin (600 mcg, 2,000% DV): Supports fatty acid metabolism, hair, skin, and nail health
• Pantothenic Acid — D-Calcium Pantothenate (100 mg, 2,000% DV): Supports adrenal function, hormone synthesis, and energy metabolism
• Vitamin C — Ascorbic Acid (40 mg, 45% DV): Antioxidant support and cofactor for B vitamin function

Supplement Facts

Suggested Use

Take 1 capsule daily with food, or as recommended by a nutritionally-informed physician.

Other Ingredients

Modified cellulose (vegetarian capsule), microcrystalline cellulose, magnesium stearate (vegetable source), silicon dioxide. Non-GMO, vegan, gluten free, soy free.

Warning: Store in a cool, dry place. Keep out of reach of children.

About Doctor's Best

Founded in 1990 by a physician, Doctor’s Best is committed to science-based nutrition — formulating supplements with clinically studied ingredients at meaningful doses. Every product is manufactured to strict quality standards, with a focus on bioavailability, purity, and efficacy. Fully Active B Complex is a prime example: no shortcuts, no inferior forms — just the most effective B vitamins your body can actually use.