Methyl Folate, 1,000 mcg, 90 Tablets, NOW Foods

1,000 mcg of Quatrefolic® (6S)-5-MTHF — the patented, biologically active form of folate that bypasses conversion, crosses the blood-brain barrier, and works directly in the body’s metabolic pathways.

Why

Most people know folate (Vitamin B9) is important — but far fewer know that the form in most supplements and fortified foods (folic acid) is a synthetic version the body must convert before it can use it. A large portion of the population carries a common genetic variation called MTHFR that makes this conversion difficult or even impossible — meaning regular folic acid may not be delivering the folate their body actually needs. Methylfolate — specifically (6S)-5-MTHF — is the form your body is trying to make from folic acid. It’s already converted, already active, and ready to work the moment you take it. NOW Foods uses Quatrefolic®, a patented glucosamine salt form of (6S)-5-MTHF with proven superior absorption compared to standard folic acid. Beyond the MTHFR angle, methylfolate matters for everyone: it’s essential for DNA synthesis, healthy cell division, neurotransmitter production, and keeping homocysteine levels in check. And unlike folic acid, it crosses the blood-brain barrier — making it directly available to support brain health and neurological function. At 1,000 mcg (1,700 mcg DFE, 425% DV) per tablet, this is a meaningful therapeutic dose in a clean, one-tablet-daily format. 90 tablets — 90-day supply.

Key Benefits

• Biologically active, metabolically ready form of folate — no conversion required
• Ideal for those with MTHFR gene variants who cannot efficiently convert folic acid
• Crosses the blood-brain barrier — supports neurological health and neurotransmitter synthesis
• Supports normal cell division and DNA synthesis
• Supports healthy homocysteine metabolism
• Supports cardiovascular health
• Supports prenatal health — folate is critical during early pregnancy
• Quatrefolic® — patented (6S)-5-MTHF glucosamine salt with superior bioavailability
• Vegan, kosher, halal, non-GMO, GMP quality assured
• 90 tablets — 90-day supply at 1 tablet daily

Formula Highlights

• Folate as Quatrefolic® (6S)-5-MTHF Glucosamine Salt — 1,000 mcg (6S)-5-MTHF / 1,700 mcg DFE per tablet (425% DV)
• Quatrefolic® — patented form with clinically proven superior bioavailability over folic acid
• Active co-enzyme form — directly utilisable without MTHFR-dependent conversion
• Crosses the blood-brain barrier — supports neurological function directly

Supplement Facts

Serving Size: 1 Tablet | Servings Per Container: 90

Suggested Use

Take 1 tablet daily with a meal.

Other Ingredients

Microcrystalline cellulose, stearic acid (vegetable source), silicon dioxide. Free from wheat, gluten, soy, milk, egg, fish, shellfish, tree nuts, and sesame. Vegan, non-GMO, kosher, halal.

About NOW Foods

Family owned since 1968, NOW Foods is one of the most trusted names in natural supplements — committed to making high-quality, affordable supplements that are GMP quality assured, rigorously tested, and never compromised on ingredients.

Warnings

For adults only. High-dose folate may mask Vitamin B12 deficiency — the elderly and those with conditions affecting B12 absorption should monitor B12 status regularly when taking this product. Consult your healthcare practitioner before use if taking phenobarbital, phenytoin, primidone, or methotrexate. Consult your healthcare practitioner before use if pregnant, breastfeeding, taking medication, or if you have a condition involving nutrient malabsorption. Keep out of reach of children. Store in a cool, dry place.