Methyl Folate, 1,000 mcg, 90 Tablets, NOW Foods

Now Foods Methyl Folate — 1,000 mcg of (6S)-5-MTHF per tablet as Quatrefolic®, the patented, most bioavailable form of folate available. The biologically active, metabolically ready form of folate that bypasses the conversion steps required by regular folic acid — essential for those with MTHFR gene variants. Crosses the blood-brain barrier to support neurological health. Vegan, kosher, halal, non-GMO. GMP quality assured. 90 tablets.

Why you need it

Most people know folate (Vitamin B9) is important — but far fewer know that the form of folate in most supplements and fortified foods (folic acid) is actually a synthetic version that your body has to convert before it can use it. And here’s the catch: a large portion of the population carries a common genetic variation called MTHFR that makes this conversion difficult or even impossible. If you’re one of them, taking regular folic acid may not be giving you the folate your body actually needs.

Methylfolate — specifically (6S)-5-MTHF — is the form your body is trying to make from folic acid. It’s already converted, already active, and ready to go to work the moment you take it. No conversion needed. Now Foods uses Quatrefolic®, a patented form of methylfolate with proven superior absorption compared to standard folic acid.

Beyond the MTHFR angle, methylfolate matters for everyone: it’s essential for DNA synthesis, healthy cell division, neurotransmitter production, and keeping homocysteine levels in check. And unlike folic acid, it can cross the blood-brain barrier — making it directly available to support brain health and neurological function in a way that regular folate simply can’t.

At 1,000 mcg (1,700 mcg DFE, 425% DV) per tablet, this is a meaningful therapeutic dose in a clean, one-tablet-daily format.

Key benefits

• Folate 1,700 mcg DFE (1,000 mcg (6S)-5-MTHF) per tablet — 425% DV
• Quatrefolic® — patented (6S)-5-MTHF glucosamine salt, superior bioavailability to folic acid
• Biologically active, metabolically ready form — no conversion required by the body
• Ideal for those with MTHFR gene variants who cannot efficiently convert folic acid
• Crosses the blood-brain barrier — supports neurological health and neurotransmitter synthesis
• Supports normal cell division and DNA synthesis
• Supports healthy homocysteine metabolism
• Supports cardiovascular health
• Supports prenatal health — folate is critical during early pregnancy
• Co-enzyme B vitamin — works directly in the body's metabolic pathways
• Vegan, kosher, halal, non-GMO
• GMP quality assured — family owned by Now Foods since 1968
• Free from wheat, gluten, soy, milk, egg, fish, shellfish, tree nuts, and sesame
• 90 tablets — 90-day supply at 1 tablet daily

Important cautions

• B12 masking: High-dose folate may mask Vitamin B-12 deficiency. The elderly and those with conditions affecting B12 absorption should monitor B12 status regularly when taking this product
• Medication interactions: Consult your physician before use if taking phenobarbital, phenytoin, primidone, or methotrexate
• Medical conditions: Consult your physician before use if you have any condition involving nutrient malabsorption
• Consult your physician before use if pregnant or breastfeeding
• For adults only

Formula

Each tablet delivers:

• Folate (from Quatrefolic® (6S)-5-MTHF Glucosamine Salt): 1,700 mcg DFE / 1,000 mcg (6S)-5-MTHF | 425% DV

Supplement facts

Serving size: 1 tablet | 90 servings per container

Other ingredients

Microcrystalline cellulose, stearic acid (vegetable source), silicon dioxide. Free from wheat, gluten, soy, milk, egg, fish, shellfish, tree nuts, and sesame. Vegan, non-GMO, kosher, halal.

Suggested use

Take 1 tablet daily with a meal. See cautions above before use.

Why trust Now Foods

Family owned since 1968, Now Foods is one of the most trusted names in natural supplements — committed to making high-quality, affordable supplements that are GMP quality assured, rigorously tested, and never compromised on ingredients.